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zara
06-22-2005, 03:45 AM
I found this info regarding alopecia treatment:

http://www.naaf.org/requestinfo/faq.asp

Cortisone injections. The most common treatment is the injection of cortisone into the bare skin patches. The injections are usually given by a dermatologist who uses a tiny needle to give multiple injections into the skin in and around the bare patches. The injections are repeated once a month. Both the needle prick and the slight tingling are usually well tolerated and there is no discomfort after leaving the doctor's office. If new hair growth occurs, it is usually visible within four weeks. Treatment, however, does not prevent new patches from developing. There are few side effects from local cortisone injections. Occasionally, temporary depressions in the skin result from the local injections, but these "dells" usually fill in by themselves.

Topical minoxidil. Five percent topical minoxidil solution applied twice daily may grow hair in alopecia areata. Scalp, eyebrows, and beard hair may respond. If scalp hair regrows completely, treatment can be stopped. Two percent topical minoxidil solution alone is not effective in alopecia areata; response may improve if cortisone cream is applied 30 minutes after the minoxidil. Topical minoxidil is safe, easy to use, and does not lower blood pressure in persons with normal blood pressure. Neither 2 percent nor 5 percent topical minoxidil solution is effective in treating those with 100 percent scalp hair loss.

Anthralin cream or ointment. Another treatment is the application of anthralin cream or ointment. Anthralin is a synthetic, tar-like substance that has been used widely for psoriasis. Anthralin is applied to the bare patches once daily and washed off after a short time, usually 30 to 60 minutes later. If new hair growth occurs, it is seen in eight to twelve weeks. Anthralin can be irritating to the skin and can cause temporary, brownish discoloration of the treated skin. By using short treatment times, skin irritation and skin staining are reduced without decreasing effectiveness. Care must be taken not to get anthralin in the eyes. Hands must be washed after applying.

Cortisone pills. Cortisone pills are sometimes given for extensive scalp hair loss. Cortisone taken internally is much stronger than local injections of cortisone into the skin. It is necessary to discuss possible side effects of cortisone pills with your physician. Healthy young adults often tolerate cortisone pills with few side effects. In general, however, cortisone pills are used in relatively few patients with alopecia areata due to health risks from prolonged use. Also, regrown hair is likely to fall out when the cortisone pills are stopped.


Topical immunotherapy. Another method of treating alopecia areata or alopecia totalis/universalis, is known as topical immunotherapy and it involves producing an allergic rash or allergic contact dermatitis. Chemicals such as diphencyprone (DPCP) or squaric acid dibutyl ester (SADBE) are applied to the scalp to produce an allergic rash which resembles poison oak or ivy. Approximately 40% of patients treated with topical immunotherapy will regrow scalp hair after about six months of treatment. Those who do successfully regrow scalp hair still need to continue the treatment to maintain the hair regrowth, at least until the disease turns itself off. An itchy rash may be uncomfortable in very hot weather, especially under a wig. These treatments are not widely available in the United States, although they are used frequently in Canada and Europe.

zara
06-22-2005, 05:50 AM
"The incidence of AA* in 39 patients with lupus erythematous was 10% in a study by Werth et al, in contrast to 0.42% of general dermatologic patients."

http://www.emedicine.com/derm/topic14.htm

*alopecia areata
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"Reversible non-scarring alopecia occurs in patients with SLE in up to 40% of patients."

Link: http://medind.nic.in/jaa/t03/i1/jaat03i1p22.pdf

Alopecia in lupus can be scarring or nonscarring, localized or generalized.