A little confused

[lullrich76]

How can my C4 be low and my CH50 be high? Shouldn't my C4 be affecting my CH50?

[wifajax]

Hi Lisa!

There are nine components to the complement system, named C1 to C9. C3 and C4 are the ones most commonly measured in lupus. CH50 is a measure of the activity of the entire complement system (C1 to C9 combined).

I guess it would be possible for C4 to be low and CH50 to be high...I'd say this is something you'll want to discuss with your doctor.

Terri