<div class='quotetop'>QUOTE(Raglet @ Jun 23 2006, 03:26 PM) Quoted post</div><div class='quotemain'> problem with me was thata they had already increased my symbicort for some a week, plus had me on 40mg pred for some days prior and also given me 500mg methylpred plus iv antihistamines imediately prior to the rituxan, so I was very loaded full of anti asthma drugs (I have asthma). It took another 24 hours to get the asthma attack undercontrol, it was pretty savage.
Basically they are doing the same run up protocol next time (same steroids, antihistimines etc) but the advise they have had was to dribble it in very slowly over 24 hours or more if necessary. The company who manufactures it and the oncologists who are more familiar with its usage say that usually they can get in in if they just dribble it in very slowly.
i don't usually have allergy problems to drugs - wow, i am amazed that you were able to go home within 4 hours, despite all the emmergency treatment they gave me i also had to have a zillion nebs over the next 24 hours so i had to stay in hospital. then i had to demonstrate that i could hold my oxygen sats without the nebulisers, so that took a bit longer too. actually i am still wheezing
did you desat (have your oxygen levels in your blood bottom out) when you had your reaction ? i am surprised that you weren't in hospital for the treatment, they won't let me have it anywhere except a hospital with a fully equipped intensive care unit (which is why i couldn't have it in the private hospital, it was the intensive care issue).
got my fingers crossed that all will go well next time (for us both)
raglet
<div class='quotetop'>QUOTE(Raglet @ Jun 24 2006, 10:11 AM) Quoted post</div><div class='quotemain'>
problem with me was thata they had already increased my symbicort for some a week, plus had me on 40mg pred for some days prior and also given me 500mg methylpred plus iv antihistamines imediately prior to the rituxan, so I was very loaded full of anti asthma drugs (I have asthma). It took another 24 hours to get the asthma attack undercontrol, it was pretty savage.
Basically they are doing the same run up protocol next time (same steroids, antihistimines etc) but the advise they have had was to dribble it in very slowly over 24 hours or more if necessary. The company who manufactures it and the oncologists who are more familiar with its usage say that usually they can get in in if they just dribble it in very slowly.
i don't usually have allergy problems to drugs - wow, i am amazed that you were able to go home within 4 hours, despite all the emmergency treatment they gave me i also had to have a zillion nebs over the next 24 hours so i had to stay in hospital. then i had to demonstrate that i could hold my oxygen sats for 4 hours without the nebulisers, so that took a bit longer too. actually i am still wheezing
did you desat (have your oxygen levels in your blood bottom out) when you had your reaction ?
got my fingers crossed that all will go well next time (for us both)
raglet
[/b][/quote]
problem with me was thata they had already increased my symbicort for some a week, plus had me on 40mg pred for some days prior and also given me 500mg methylpred plus iv antihistamines imediately prior to the rituxan, so I was very loaded full of anti asthma drugs (I have asthma). It took another 24 hours to get the asthma attack undercontrol, it was pretty savage.
Basically they are doing the same run up protocol next time (same steroids, antihistimines etc) but the advise they have had was to dribble it in very slowly over 24 hours or more if necessary. The company who manufactures it and the oncologists who are more familiar with its usage say that usually they can get in in if they just dribble it in very slowly.
i don't usually have allergy problems to drugs - wow, i am amazed that you were able to go home within 4 hours, despite all the emmergency treatment they gave me i also had to have a zillion nebs over the next 24 hours so i had to stay in hospital. then i had to demonstrate that i could hold my oxygen sats without the nebulisers, so that took a bit longer too. actually i am still wheezing
did you desat (have your oxygen levels in your blood bottom out) when you had your reaction ?
got my fingers crossed that all will go well next time (for us both)
raglet
sorry, the editing controls on this board are not working properly - i tried to edit out saying i was surprised you weren't in hospital (I see that you were) but it just kept putting a quote in
aaaarrrrgggghhhhhh !!!!!!!! [/b][/quote]
Dear Raglet
Some days are just like that (editing controls). At the risk of scaring the heck out of others reading this, I must say our reactions are rather rare. In the proper setting, these reactions are controllable.
I was in the hospital, but in the Cancer Center infusion room. They infuse Rituxan routinely for lymphoma patients. Most of the folks in there with me were looking at a much more desperate future than I. I was not the only person there on rituxan iv that day.
I am allergic to penicillin, naproxan sodium (rules out using any of the NSAIDS), aspirin, and cephalosporin antibiotics in general. They all send me to the hospital in dire straits. I don't have much of an asthma reaction however. I flare bright red all over, my entire body swells, my throat and airways close, and blood pressure drops. That all happens in about 2 minutes. Living on the edge. style_emoticons/<#EMO_DIR#>/sorry.gif Just recently, I flared up with fentanyl patch...so I can add that to the list. I had to peel the thing off and go through opioid withdrawal with no taper...not pretty.
My blood O2 was already extremely low from SLE pneumonitis (I did not exchange oxygen very well). I had a driver take me home, so I was not alone when I left. Also, because of my other drug allergies, I have a closet full of meds for emergency use with allergic shock....can't wait for the ambulance!
I had been on 60mg pred for weeks going in to this spiked with 1000mg pulses....plus max doses of Imuran & Plaquenil. Shudder. After treatments, I tapered off the Imuran and Plaquenil rapidly. I just finished tapering prednisone two weeks ago....it took a long long time.
My first full treatment was dripped over 10 hours, then each of the others was tapered faster until the last one was finished in three hours. The nurse began each session with a slow drip and turned it up every half hour throughout the treatment. I must say that the nurses watched me like a hawk, and I was hooked up to monitors. I had no problems at all after the first little mess. style_emoticons/<#EMO_DIR#>/ok.gif
I am hoping to hear all has gone well for you, and that you are feeling better. You had a wild time of it. It is definitely your turn to be well! style_emoticons/<#EMO_DIR#>/smile.gif
Best Wishes.....Fran