Sub-acute cutaneous lupus erythematosus (SCLE) - A nonscarring
rash that can coexist with both discoid & systemic lupus, but
may be a 'bridge' between discoid lupus & SLE.
SCLE is sometimes described as a disease midway between SLE and
DLE, & it can coexist with both SLE and DLE.
SCLE appears to affect primarily white females.
It is a rash seen in about 9% of lupus patients; 20% with SCLE
also have lesions typical of discoid lupus. SCLE doesn't scar the
skin, & the lesions do not usually itch.
85% of people affected by SCLE (85%) are extremely photosensitive.
Approximately 70% of people affected by SCLE have a positve test
for anti-Ro (SSA).
60 to 81% of patients with SCLE have positive ANAs, but only about
50% of the positive ANAs are of a significant titer.
Cutaneous vasculitis is a common occurrance with SCLE.
SCLE is treated using antimalarials, steroids, cytotoxic drugs,
sunprotection, & cortisone creams.
Although usually a disease of benign nature, some SCLE patients
develop severe life-threatening disease.