Hi, Well I went to the lab and got copies of my bloodwork. The doctor ordered an AMA but lab accidentally did an ANA. The past four days I have been thinking my AMA was that high and that I had primary biliary cirrhosis. This is crazy. It makes much more sense though. I have been tested numerous times for lupus and many doctors have suspected I could have it but ESR and ANA always came back fine. I have dealt with debilitating pain at times and constant skin rashes since my early 20's. Constant fatigue and no energy (my husband always thinks I am depressed because I am so trired). I had a really complicated pregnancy which when I read about lupus and pregnancy describes mine to a tee (preeclampsia, placental infarctions, bedrest, growth restriction of baby, premature delivery). I know that just an ANA cannot diagnose anything but what do you make of an ANA that high. Am I on the road to finally get a diagnosis? As much as I don't want to have anything wrong with me, I am sick of feeling this way and not knowing why.