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Hi everyone.

I found this article and thought I would share it. I don't remember if anyone has already shared it, please forgive me if I have repeated something.

B Cells Can Act Alone in Autoimmune Diseases

August 7 (HealthDay News) -- B cells may be more responsible for causing autoimmune diseases like lupus or rheumatoid arthritis than initially thought, according to a new study.
The finding, published in the Aug. 7 online issue of the journal Immunity, may give scientists a new path to pursue in finding ways to stop the immune system's chronic attacks on the body's own tissue during these diseases.
B cells, the source of damaging auto-antibodies, have long been thought to remain quiet in autoimmune diseases unless they are given a kick-start by T-cells. Researchers from Yale and Boston universities had found that toll-like receptors recognize and react to "self" molecules, in particular mammalian DNA and RNA. When this occurs, these receptors help activate B cells that make the classical auto-antibodies of lupus.
These signals, like those from T-cells, start the autoimmune process in B cells. In the new study, the researchers theorize that once activated in this way, the B cells can subsequently recruit T-cells. This creates a "vicious cycle" of chronic autoimmune disease in which the two types of cell prod each other into action.
The findings could explain why autoimmune-disease treatments aimed at T-cells have not done as well as those targeting B cells, the researchers said.

SOURCE: Yale University, news release, Aug. 7, 2008


Here is the web page.

http://yourtotalhealth.ivillage.com/b-cells-can-act-alone-in-autoimmune-diseases.html

If you click on autoimmune illness, it will take you to quite a few news articles.

:grouphug2:
Lyn
 
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