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Hi Meryl

I have read that the ANA can fluctuate and sometimes someone being positive for years can be negative and also there are some that are negative and still have Lupus. The way I think they look at ANA is as a guiding tool. If it is positive and you have symtpoms then there is more weight towards lupus. If you have other positive bloods and symptoms, I don't think they would be too concerned that the ANA is negative . Sometimes with treatment ANA can go back to negative.

Let us know what your doctor's explanatino is.
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