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DILE Drug induced Lupus Erythematosis

3929 Views 41 Replies 27 Participants Last post by  paperbagprincessNZ
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By definition, drug induced lupus goes when the medicine implicated is withdrawn - and would recur if the drug is taken again. DILE is treated as necessary like lupus depending on the symptoms.
Some drugs trigger clinical lupus. Many common medicines might trigger lupus indirectly by increasing photosensitivity.

Of course we all like to know what might have caused our lupus but it doesn't make much difference in practice.

Drugs like Remicade and Enbrel tend to be used cautiously because they can cause ds DNA antibodies which is a concern ,although I haven't seen any reference to clinical lupus resulting.

Cheers
Clare
About the TNF drugs like Enbrel or Remicade this article seems to sum up the general view about people with lupus using them. I haven't found anything online to suggest that this view has been revised but it is increasing hard to find reliable up to date information online as they are limiting access these days, either by only allowing doctors or institutions access or charging for access

http://www.arthritispharmacy.com/ar...IS_DRUG_LINKED_TO_RARE_LUPUS_SIDE_EFFECT.html

Most doctors play safe and won't use these drugs for lupus if there are alternatives, but there've got to be times when these drugs are worth trying.

Cheers
Clare
Minocycline Induced lupus

Something worth noting if you know a teen who starts having lupus like symtpoms and is on minocycline.

http://www.uklupus.co.uk/mino.html

http://pediatrics.aappublications.org/cgi/content/full/101/5/926

http://www.med.ucla.edu/modules/wfsection/article.php?articleid=39

If the symptoms go when the drug is stopped then it's drug induced but it seems that in a few predisposed people clinical lupus is triggered.

It seems that in some places a warning of the possibility is noted on the packaging. Even if it is rare, there should be a general warning as this is for all side effects howver unlikely.

Clare
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Hi Brenda

:)

I'm wondering why you mention diclofenac.

Cheers
Clare
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