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I have no idea about dRVVT levels but abnormal results might figure in the diagnosis of lupus, associated or not with high levels of anticardiolipin antibodies. They both have to do with the antiphospholipid antibodies
There are several tests for so called Lupus Anticoagulant - the dilute Russel Viper Venom time is only one of them.

The presence of these antibodies would lead to a diagnosis of Antiphospholipid Syndrome
(APS) only if there have been associated clotting incidents. The sort of statistic I have read is that about one third of those with lupus have these antibodies but only one third of those actually suffer from them

Both the LA tests and tests for anti cardiolipins should be done twice at the same time because levels can vary. The interval between testings is given from between at least 6 weeks to 12 weeks.


From ACR Criteria List
Immunologic disorder
a) Anti- ds-DNA: antibody to native DNA in abnormal titer
OR
B) Anti-Sm: presence of antibody to Sm nuclear antigen
OR
c) False positive serologic test for syphilis known to be positive for at least 6 months and confirmed by Treponema pallidum immobilization or fluorescent treponemal antibody absorption test
d) Positive finding of antiphospholipid antibodies based on 1) an abnormal serum level of IgG or IgM anticardiolipin antibodies, 2) a positive test result for lupus anticoagulant using a standard method, or 3) a false-positive serologic test for syphilis known to be positive for at least 6 months and confirmed by Treponema pallidum immobilization or fluorescent treponemal antibody absorption tes
:)
Clare
 
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