When I was first put on neurontin, I was having what were diagnosed as migraneous giganticus. The neurologist I was seeing then: Steward Tepper, MD, was still in Seattle. He has since moved to CT, their gain, our loss. He told me that research had shown that it was safe to take up to 13,000 mgs daily. I was taking 1,600 mgs 5 X a day. I now take 1,600 mgs twice a day, up it if I need to. Rarely do I need to add in another dose any more.
I often need to take higher than usual doses of meds due to scaring in my small intestine from celiac disease. The scar tissue doesn't absorb like a normal small intestine does so large amounts are needed to get a therapeutic amount absorbed.
Considering the **** my life was in with the extended migraines, any relief was welcome!
I also have peripheral neuropathy in both legs and mildly in my hands. I have very little feeling in my left leg and foot below the knee and about 1/2 damage in my right leg below the knee. I didn't make a connection with the neurontin for this, but must admit it may help there too. I don't skip any doses, so don't have comparison with or without.