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Discussion Starter · #1 ·
Has anyones blood work come back with extremely high IgM
or Immunoglobulin M,Qn, Serum? Mine is 3x the high values and my doctor didn't mention it as a concern. I have to make an appt to talk with her but I was looking it up and it sounds concerning. Does anyone know about this blood test and the results. Any help or insight is as always appreciated!!:)
 

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My IMg is always very high (Dr should retest in 6 weeks to compare results). My Rhumy has told me I have APS, but that without the Lupus Anti-Coagulent, it is considered mild. I take a baby asprin every day and they check the results every 6 weeks to make sure they aren't going any hight.

I am not a Dr and am not sure that your results mean the same or if they mean anything. I would definately ask the Dr what he thinks may have caused this, and if you should be concerned about it.

Is your Dr a Rhumy? If not, I would want to see a specialist.

Hope this helps...
Stephanie
 

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Discussion Starter · #3 ·
thanks Stephanie I do see a rheumy and I have a call into her right now for more info never saw it before so I thought I would ask others about it. What is APS? My rheumy had me on baby aspirin since Sept I figured it was for inflammation but maybe its to thin the blood which is something I saw could be a result of this being high.
Thanks for the info and for the reply!!:)
 

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I'm sorry I don't know about IgM but I think your doctor should be able to give you a simple explanation, enough to allay your concerns anyway.

A test result only has signifcance when viewed along with other test results and symptoms. This IgM seems to be often associated with infectious diseases so maybe your levels are high because of some recent infection but this is just me speculating

APS is a blood clotting condition and everybody with a lupus diagnosis should be tested for it if they were not already as part of the diagnostic testing.
APS stands for anti phospholipid syndrome.
The two main tests are for anticardiolipin antibodies, and then clotting tests for something called "lupus anticoagulant". The name was given because this was first identified in lupus patients but in fact more people have this abnormality without having lupus. There are some other tests that help determine if the high levels are due to autoimmune disease or infectious diseases which can give false positives, for lupus. About one third of people with lupus have the antibodies and about one third suffer from the strokes or thrombosis or repeated miscarriages that would lead to a diagnosis of APS, or so I have read.
If you have not suffered such symptoms you technically do not get an APS diagnosis, however there can be many other associated symptoms, such as headaches and cognitive problems.
The presence of the antibodies can also count towards a lupus diagnosis, see ACR Criteria.
Levels can be raised from time to time for other reasons, or either might be negative or not significantly high so usually both tests are run at an interval of at least six weeks.

Treatment is with blood thinners when there have been major associated incidents but aspirin is often given to try to thin the blood a bit in the hope of avoiding major problems occuring. Plaquenil has a role to play too as it slightly thins the blood and can often help with some of the associated symptoms. Many of us are on low dose aspirin ( about 75mgs a day) for several other reasons such as the very high risk of cardiac and artery disease in women with lupus. Any pain killing effects of the aspirin are incidental because there are much better ways of dealing with pain. At such a low dose I shouldn't think it would make that much difference to the sort of chronic joint pain suffered in lupus.

Cheers

Clare
 

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Discussion Starter · #5 ·
Thanks Clare I don't see those tests on my results so I will ask my doctor BUT what is weird is that for the past 3 months I have been having terrible headaches some are even migraines and that is something new for me (I had migraines over 10 +) yrs ago but they said it was due to my birth control which I haven't been on since then.
I do take a low dose aspirin everyday since she told me to in Oct last yr. I will be starting Cellcept and metho tomorrow waiting for pharmacy to fill hopefully this will help I can't take Plaqniel due to being a high risk for detatched retina.
I have a call into the Rheumy for more info regarding these results, I wouldn't be concerned if I felt the way I usually do during a flare but its bad it feels like I did over 2+ yrs ago before I was diagnosed and put on meds.
UGHHHHHH!!!!:mad: :mad: :mad: :mad:
Thanks for your reply and info!! :)
 
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