[cispence98]

Hi all...Been sick and not around much. I went to Rheumy and my antidsdna is not high so unfortunately its not a lupus flare (that would make sense) I have been having fevers of over 100 for 2 days not consistent though my normal temp is 97.5 baseline. Anyway my blood work for over 2 years every 3 months have my IGM high twice the high limits, so I have been looking it up and found Hyper IGM, has anyone ever heard of this? It also presents itself with a high ANA but my doctor just says its inflamation nothing I have read refers to IGM as imflammation (sp) so I am confused. I also don't feel good all my labs are crazy
high IGM high wbc high MCV low Bun Creatine High C reactive protien and others I can't remember, ANYWAYS I am asking if any one has any thoughts or opinions re this I have also show traces of protien in urine for over 2 yrs but I guess its ok cause DR doesn't seem to concerned with all these abnormal labs I just can't convince myself its a fibro flare, I am soooo confused and soo not feeling good, any thoughts are appreciated!!
I hope all is well!!

 

[Maia]

Have they tested you for mononucleosis yet? High IgM can be found with this and it can present in much that way overall. Although I wouldn't think it would keep the IgM high for two years, which I think is what you're saying.

Oh, and ds-dna cannot be relied upon to determine if you are having a lupus flare. It's far from a high correlation - and can be raised during periods of relative wellness and lowered when in an acute flare.

Low BUN and creatinine are actually good things to have Means you are well hydrated (usually) and your kidneys are working exceptionally well respectively.

As for hyper-IGM, what I have read about it is that you would normally also be found to have low IGA and IGG levels, and most typically will have low neutrophil counts. It is also a very rare immune disorder, and would usually have been diagnosed in early childhood if not infancy due to recurrent infections. If you're really concerned, I would ask your doctor about it, or about why he believes the IgM is raised due to inflammation only.

 

[forever hopeful]

my normal temperature is around 97.5 too. do you often get doctors or nurses saying oh well your temp is 98.8 or 99.8 that's good? it frustrates me because i know that if my temperature is a higher than 97.5 that i have a low grade fever. have you ever mentioned this to any of them and if so what have they said to you??