Have they tested you for mononucleosis yet? High IgM can be found with this and it can present in much that way overall. Although I wouldn't think it would keep the IgM high for two years, which I think is what you're saying.
Oh, and ds-dna cannot be relied upon to determine if you are having a lupus flare. It's far from a high correlation - and can be raised during periods of relative wellness and lowered when in an acute flare.
Low BUN and creatinine are actually good things to have
Means you are well hydrated (usually) and your kidneys are working exceptionally well respectively.
As for hyper-IGM, what I have read about it is that you would normally also be found to have low IGA and IGG levels, and most typically will have low neutrophil counts. It is also a very rare immune disorder, and would usually have been diagnosed in early childhood if not infancy due to recurrent infections. If you're really concerned, I would ask your doctor about it, or about why he believes the IgM is raised due to inflammation only.
Oh, and ds-dna cannot be relied upon to determine if you are having a lupus flare. It's far from a high correlation - and can be raised during periods of relative wellness and lowered when in an acute flare.
Low BUN and creatinine are actually good things to have
As for hyper-IGM, what I have read about it is that you would normally also be found to have low IGA and IGG levels, and most typically will have low neutrophil counts. It is also a very rare immune disorder, and would usually have been diagnosed in early childhood if not infancy due to recurrent infections. If you're really concerned, I would ask your doctor about it, or about why he believes the IgM is raised due to inflammation only.