Hello Karol
The recommendation varies but 200mgs morning and evening is the usual. What people do varies too, but
your doctor should be advising
you ! After all she is responsible for your well being and you do have particular concerns.
I have been taking all my meds at once for years now, because I am less likely to forget the evening doses and there's no reason why I shouldn't take them together nor any reason why I should take these meds at specific times each day, as there is with some meds. The general theory is that it is better to maintain a continuous supply than all in one go.
The one thing that makes very good sense is to start on a low dose and gradually work up to the recommended dose. You could even try every other day. Your body will have the chance to get used to it and any of the common side effects will be less, and more serious side effects likely to be detected early on but easier to get it out of your system. I have read that it's better for some people not to take antimalarials in the evening because they can have a stimulating effect, especially Quinacrine.
Good Luck!

Clare