Building your imuran dose up from 50 mgs to 150 over a few days is best yes, as it helps your body get used to the med and helps you avoid any tummy upset. Given your reaction to plaquenil it might also be an idea to not take imuran on an empty stomach until for the first few days.
If you do experience any tummy upset do not panic and stop the imuran suddenly, but rather call your doc and let her know you're having a problem; there's meds you can take (such as omeprazole) with imuran for a few days that will in all likehood calm your stomach upset. Nonetheless, side-effects from imuran are extremely rare and so really it's more than likely that you'll have absolutely no problems with it!
I started Imuran on 25mgs every other day for a week, then 25 mgs every day for a week increasing by 25mgs in this way until I got to the full dose. I was told to take it after supper.
I hope it helps you
I was just switched from MTX injections to Imuran. I wanted off the MTX because the side effects were becoming a major problem. My RD said to take two a day for two weeks and if there's no problem, go up to three a day.
Can anyone tell me if Imuran is less toxic than MTX?
Hi, I just switched from methotrexate to Imuran this week also. My rheum wants me to start out at 1/2 a pill (I think that is 25 mg) and increase 1/2 pill every 2 weeks. She thinks this is rather fast then she would usually prescribe but wants to get me on a high dose quick. I'm suprised you are supposed to take that much to start out with.
Sheira, I saw my PCP yesterday and he said it would be OK to start with one a day and gradually work up from there, even though the RD's prescription says start with 2 a day for two weeks, then go to three. Your prescription is even tougher to start. I'd ask your doctor is it's OK for you to start more slowly, since Imuran is known to give stomach problems. Good luck!