Hi there, I was on Imuran, and for several months was fine, then one day I felt too week to get out of bed, hby just thought I was tired. On the second day hby called the dr. he said to get a hematologist to check my bloods. By the time we got to his office, he just took a quick check, and put me in the hospital, I needed 3 pts. of blood, he said it deffinately the imuran. But, we are all different. just keep up with your blood tests.