An interesting article which deals with the challenges faced by researchers due to the lack of patients for clinical studies. If you read through there will be an LFA live chat on the subject too.
http://www.reuters.com/article/pressRelease/idUS19302+02-Sep-2009+BW20090902
http://www.reuters.com/article/pressRelease/idUS19302+02-Sep-2009+BW20090902