what i can say is that tests are the key to confirm lupus, but they are not the first step ....first you have to cnsider your symptoms and how you feel. I am no expert, but i'd say that lupus without ANA, ENA, and C3 C4 should be considered in a second place...there r other diseases that may cause similar symptoms letting thos blood works normal...so i'd say keep asking, but maybe about somethin' else...