Hello all. I'm new here and I'd like to hear what you can tell me about lupus and brain fog. I've had major brain fog for the past six months and I thought it was because of the MTX I was on. I was recently switched to Imuran and I'm hoping the brain fog will go away, but now I just read that there is also a lupus brain fog. Geeze! Can you enlighten me about this? Maybe I can figure out where the heck mine's coming from.