Lupus and TB susceptible people

266 Views 8 Replies 6 Participants Last post by Merle, Mar 24, 2009

x_claire_x

Discussion Starter · Mar 24, 2009

Hi, a question for my learned friends! My very highly qualified homeopath suggested to me that it has been known for some time within her profession that those genetically susceptible to TB are also susceptible to Lupus. Now she went on to state that TB was often found in higher numbers in certain areas geographically... I felt I had no link to lupus, my mother was adopted, but her mum was an underage irish schoolgirl who came over here to have the baby and gave her up for adoption. The homeopath said there were areas in Ireland that had high TB rates and I could be genetically linked to those areas.... ANYWAY the strange thing is that before this discussion she had no way of knowing my sister had TB at the age of 3, she made it, just... so was very lucky as treatments were scarce at that time...
Wondered if any of you have any thoughts or comments, it intrigues me!

Thanks,
Claire

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Joandublin

· #5 · Mar 24, 2009

Hi Claire

You got me googling :hehe:... I found something that might interest you about the possibility of human gene variants and susceptibility to TB.

http://www.bio-medicine.org/medicin...-Be-Due-To-Three-Human-Gene-Variants-11606-1/

I still havent found anything that might link these specific gene variants to those gene variants that were found to increase the risk of developing Lupus. Here's a link to the Lupus gene research which might interest you.

http://www.sciencedaily.com/releases/2007/12/071202155309.htm

Its all way over my head but if it floats your boat I will let you delve into the research and come up with some hypothesis!! :hehe:

Go girl go......

Luv n stuff
Joan:rose:

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Joandublin

· #8 · Mar 24, 2009

Claire

Here's another link. Its only an abstract and you would have to sign up to get the full text though. Not sure who is 'allowed' to sign up. You probably have to be in a research organisation.

http://www3.interscience.wiley.com/journal/117879016/abstract?CRETRY=1&SRETRY=0

And here's a more interesting one published online last month from Trinity College Dublin. It focuses on genetic variations of Toll-Like Receptors (TLR's) and their link to disease susceptibility and cites both TB and SLE.

http://content.karger.com/ProdukteD...t&ArtikelNr=200774&Ausgabe=0&ProduktNr=234234

Happy reading :hehe: Check out the bibliography on the last one as well. Might be interesting research

Cheers
Joan:rose:

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