my rheumy just started me on methotrexate for the first time ever. We are hoping that this is going to help my severe joint problems. He has started me on 7.5mg for two weeks and then 10mg for two weeks and then I am supposed to see him. I also have to take folate on my off days. Can any of you give me some feedback regarding side effects and how quickly the meds make take effect? I know what I can read but would love some "real life" experience.