I am on methotrexate and plaquenil both , and have been on them for many,many months (read years for the plaq.). The MTX is for my arthritis etc. pains , and the Plaquenil is for my inflammation of my lung and heart linings as I understand it anyways.
I was on Imuran , but that was stopped when I went on methotrexate. Have tried other drugs with this combination ... such as sulfasalazine.
All the best to everyone.