Hi Margie,
Yes thats very possible because Plaquenil changes the pH of our cells and can inhibit the formation of antibodies.
Hope you are doing ok?
I have found that my doctor goes more on how I feel rather than my test results these days, that seems to be a better indicator than anything else for me. ANA is helpful for diagnosis but doesnt always indicate how we are feeling with our Lupus.
love
Lily