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Before taking Imuran, did anyone have a Prometheus blood test that would indicate how well the Imuran would work? I just got my results which is a 26.6. Does anyone know what their result was and how well the Imuran worked for them? Thanks!
 

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Hi threre,

I had the test done and mine back at 21 which is classed as low. My dermy started me on 25mgs of Imuran and then upped it to 50mgs after 3 months. I was on this for about 9 months in total and I'm afraid that it didn't do anything for me. (I have lupus discoid). Everyone is different, so I do hope it really works for you as it has helped many people here.

All the best, love Maria x
 

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Tpmt

Hello Leah :)
I think this is known as TMPT test in the UK, Prometheus being the name of the lab that markets it in the USA. Anyway it n ot only to see if the AZA will work but if there will be serious side effects and to indicate dosage recommendations depending on the enzyme levels. I found this UK site that gives levels but another site says that no reference range can be given because it varies from lab to lab etc etc.

According to this reference range, 21 and 26 would be a partial deficiency
6-34 nmol/g g/HL/hr.

http://www.southend.nhs.uk/pathologyhandbook/test_directory/tindex/tpmt.htm

Usually the significance of abnormal bloods is explained on the blood test results sheet.
As for Imuran in general, many people find it very helpful. It is usually advisable to start taking it at low doses and very gradually work up, to avoid nausea and sickness. Very regular blood work is important to check for unacceptable side effects


I pray that everything continues to go so well for you ((( Leah)))

All the best
Clare
 

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Hi Leah,
I'm in the UK, so it was explained slightly differently, but I'm also partially deficient in the required enzyme. It meant that I had to take a lower dose, but it also means that you need less of the drug to have the same effect, so hopefully it still has a good chance of working well for you.
:hehe:
 
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