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Discussion Starter · #1 ·
I wanted to know if the sed rate and CRP blood tests are the same. From what I understand they are 2 different tests that measure inflammation the body. My Rheumy's nurse said that they are the same and since the CRP test was done, no need for the SED Rate test.
Please help me with this one?
 

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Hello Ceenic

:) As far as I know they are both taken, SED and CRP. CRP tends not to be raised in lupus, according to several authorities, and if it is, it might indicate infection is present in non diagnosed or the cause of symptoms in already diagnosed.
It can be hard to distinguish between problems caused by lupus and those caused by infections, which need different treatment. I can't work out why only one would be considered enough- CRP has other uses too.


Maybe it's based on some new revelation :lol:

Cheers
Clare
 

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My understanding is they are 2 different tests. I just looked at my blood work and I always get tested for both. Another reason why you may want to go to U of Miami, just food for thought.:lol::wink2:
 

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Hi, they are 2 different tests and useful in different ways. It is interesting that only one test was ordered.

Deb x
 

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The simple answer is that they're both measures of inflammation with a different time scale.

CRP is thought to peak around 48h with a short half life (~16h). Elevation of CRP in SLE is, as stated above, not a very specific finding. ESR rises at a slower pace. There are even more reasons why your ESR can be elevated.

Choosing to order one over the other (or choosing both) is a decision involving a great deal of subtlety. There are a ton of studies trying to tease out which one is best to follow in SLE, but (to my knowledge) no solid guideline has emerged on which to follow.
 

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Discussion Starter · #6 ·
I do agree that they are different tests. I do think that they should have done the SEd Rate in addition to the CRP and all the other tests. They have done so many blood tests, what's 1 more? Karol, you are so right, I will have to make that appt. faster then I thought. Thanks for everyone's input. i just thought it was something that I misunderstood.:hehe:
 

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a ton of studies trying to tease out which one is best to follow in SLE
I don't think following CRP in SLE would help anyone, it's not very common for Lupus patients to have a raised CRP. Those with crossover diseases (say RA + SLE) it could indicate a rise in their RA activity. For the straight SLE patient it's often not much use.

ESR is not the be all and end all either, there are quite a few of us who never have a raised ESR. This causes a lot of problems during diagnosis sometimes, especially at GP level. It's often one of the first tests they run and if it is not elevated then uneducated GP's think there is no inflammation. No inflammation = no referral to a specialist :rolleyes: = unnecessary suffering and sometimes organ damage before the penny drops.

love
Lily
 

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Lily your post makes a lot of sense. For me, my Sed Rate and ESR are typically and most often very close to normal and yet other numbers can be through the roof so your right here in what your saying. :wink2::wink2::wink2:
 
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