I had to stop taking metho because my ALT's and AST's were almost 200. I had to have a liver biopsy (which did not hurt). All was well with that and gastro doc put me a drug to protect my liver Urso forte. I was switched to another chemo drug called cytoxin. It took about 2 or 3 months to get liver enzimes back to normal. They have been normal ever since .
Sorry about the font size. Having trouble with some of key on computer.