hey love, i am on exactly the same meds, plaquenil, methotrexate..plus a few others and just restarted prednisolone 35mg daily and i seem to be weeing alot too...i usually wee a fair amount but its majorly increased at mo...im wondering if it could be a uti as i have lower back pain too...because methotrexate + steroids = immunocompromised!! im also having serious headache issues too though altho that could be the stress from work which has caused this flare anyway!! How come they put you on pred? was the mtx not working? lots of love xxxxxx