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Doxepin Hydrochloride 


Brand names - Adapin, Sinequan, Dothiepin

Medication type - Tricyclic antidepressant.

Common side effects - Drowsiness or dizziness, headache, dry mouth or unpleasant taste, fatigue, heightened sensitivity to light, weight gain, nausea, increased appetite.

Rare side effects - Heartburn, difficulty sleeping, diarrhoea, increased sweating, vomiting.

Serious side effects - Confusion, heartbeat irregularities, hallucinations, seizures, extreme fatigue or drowsiness, blurred or altered vision, breathing difficulty, constipation, impaired concentration, difficult urination, fever, extreme and persistent restlessness, loss of coordination and balance, difficulty swallowing or speaking, dilated pupils, eye pain, fainting. Also trembling, shaking, weakness, and stiffness in the extremities; shuffling gait. Call your doctor immediately.

Uses - To relieve symptoms of major depression.

Other notes - Can take 1-6 weeks to take effect. Take with food to reduce the chance of a stomach upset, unless your doctor instructs otherwise. Increase intake of fiber and fluids. When taking the oral solution, dilute doxepin in half a glass of water, milk, or fruit juice, but not grapefruit juice. Do not take this drug with a carbonated beverage. Avoid alcohol. Doxepin passes into breast milk; do not use it while nursing. Doxepin has been found to cause drowsiness in the infant. This is a potentially dangerous drug, especially if taken in excess. Tricyclic antidepressants should not be within easy reach of suicidal patients. If dry mouth occurs, use sugarless gum or candy.




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